Large Scale Localization of Protein Phosphorylation by Use of Electron Capture Dissociation Mass Spectrometry
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چکیده
Copyright © 2009, The American Society for Biochemistry and Molecular Biology Large Scale Localization of Protein Phosphorylation by Use of Electron Capture Dissociation Mass Spectrometry * Steve M. M. Sweet,‡§ Christopher M. Bailey,‡§ Debbie L. Cunningham,‡§ John K. Heath,‡§ and Helen J. Cooper§¶ From the ‡Cancer Research UK Growth Factor Group, §School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom ¶To whom correspondence should be addressed. Tel.: 44-121-414-7527; Fax: 44-121-414-5925; E-mail: [email protected] Received September 26, 2008; Revised December 19, 2008. Author's Choice Final Version Full Access Creative Commons Attribution Non-Commercial License applies to Author Choice Articles
منابع مشابه
Large Scale Localization of Protein Phosphorylation by Use of Electron Capture Dissociation Mass Spectrometry *S⃞
We used on-line electron capture dissociation (ECD) for the large scale identification and localization of sites of phosphorylation. Each FT-ICR ECD event was paired with a linear ion trap collision-induced dissociation (CID) event, allowing a direct comparison of the relative merits of ECD and CID for phosphopeptide identification and site localization. Linear ion trap CID was shown to be most...
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